ABSTRACT
Objective@#To explore the intervention effect of sports combined with group psychological counseling on the psychological craving, addiction sererity, as well as comorbid depression with anxiety severity of college students with smartphone addiction.@*Methods@#Totally 148 smart-phone addicts were randomly divided into 3 groups(sports group 49 students, group psychological counseling group 50 students, sports group counseling group 49 students). Smartphone addiction was evaluated by using the University Student Smartphone Addiction Scale(SAS-C); the degree of mental hunger was assessed by the Visual Analog Scale(VAS); the Hamilton Depression Scale(HAMD) and the Hamilton Anxiety Scale(HAMA) were used to evaluate the degree of anxiety and depression. All scales were evaluated before intervention, after intervention and 3 months after the intervention.@*Results@#The SAS-C,VAS,HAMD,HAMA scores of the three groups decreased with time(F=36.05，38.54，37.27，39.27，P<0.01), and the scores were the lowest in the sports group counseling group, SAS-C,VAS,HAMD,HAMA followed by the group counseling group and the highest in the sports group(F=34.33，32.36，32.34，34.96，P<0.01). Howevey, all the 3 groups still had depression and anxiety symptoms after 3 months of intervention.@*Conclusion@#Sports, group psychological counseling, sports combined with group counseling can all differentially help decreasing the psychological cravings and addiction levels of smartphone addicts and severity of depression and anxiety with the latter shows the highest effectiveness, followed by the group counseling and sports intervention alone.
ABSTRACT
Objective To study the changes of endotoxin in blood,Escherichia coli,lactobacillus,bifidobacterium,enterococci in feces of HCC patients.Methods Real-time fluorescence quantitative PCR was used to detect the difference between HCC group and normal group in the expression in bifidobacterium,lactobacillus,enterococcus and Escherichia coli,and the difference of endotoxin level.Results The expression levels of Escherichia coli and enterococcus in HCC group were significantly higher than those in normal control group (P＜ 0.05).Bifidobacterium and lactobacillus in primary liver cancer group significantly decreased compared with the normal group (P ＜ 0.05).The serum endotoxin level in HCC group was significantly higher than that in normal control group (P ＜ 0.05).Bifidobacterium and lactobacillus increased in HCC group.Enterococcus and escherichia coli decreased in HCC group.There was a significant positive correlation between endotoxin content and tumor number and tumor diameter in HCC patients.Conclusion Bifidobacterium,lactobacillus decreased,enterococcus and Escherichia coli increased in HCC patients.These changes along with the increase of endotoxin may relate to the development of HCC.
ABSTRACT
Objective To investigate the effects of different DO2-directed hemodynamic man-agement on postoperative prognosis of orthotopic liver transplantation (OLT)patients with different degrees of liver function insufficiency.Methods Seventy patients (male 48 cases,female 22 cases, aged 37-66 years,ASA grade Ⅲ or Ⅳ)scheduled non veno-venous bypass OLT were divided into two groups (n = 35 each ).The oxygen delivery (DO2 )maintained respectively between 350 ml·min-1 ·m-2 and 500 ml·min-1 ·m-2 (group control)and more than 500 ml·min-1 ·m-2 (group study).After induction of anesthesia,the left radial artery was cannulated,allowing continu-ous blood pressure monitoring as well as serial blood sampling,then the Swan-Ganz catheter was in-serted via the right internal jugular vein to continuously monitor CI and S-vO2 .After anesthesia induc-tion and before operation (T1 ),10 min before anhepatic phase (T2 ),30 min after onset of anhepatic phase (T3 ),30 min after neohepatic phase (T4 )and the end of surgical procedure (T5 ),the SaO2 , PaO2 ,Hb,CI and S-vO2 were recorded to calculate the DO2 ,VO2 and ERO2 .Postoperatively,ICU and hospital length of stay,quality of life (QOL)and 1-5 year survival rate were recorded.Results In the two groups,CI,DO2 and VO2 declined at T3 to a statistically significant degree in comparison with T1 (P <0.05).CI,DO2 and VO2 in group study significantly higher than those of group control (P <0.05).ERO2 in group study was lower than that of group control significantly (P <0.05).ICU and hospital length of stay were significantly shorten in group study in comparison with group control (P <0.05).Survival rate and QOL in group study tended to be slightly higher than those of group control until the end of study period,but there was no significant difference.Conclusion The DO2-directed hemodynamic management can improve prognosis with enhanced DO2 in OLT patients with different degrees of hepatic insufficiency.It has a positive impact on their outcome of shortening ICU stay and the hospitalization days.